1. a) Differentiate between glyoxisomes and peroxisomes and give their important functions.
b) Describe the process of anomerisation taking glucose as the representative example.
2. a) Write five chemical reactions which justify the pentahydroxy structure of glucose.
b) What are ketone bodies? How are these produced in the body? What does their presence in the body signify?
3. a) Name the different components of the cell membrane and state its functions. Who gave the fluid mosaic model of structure of cell membrane?
b) What is the most common form of DNA? Explain the nature of forces responsible for holding the double helix together.
4. a) What is the role of hydrophobic interactions in protein folding. Differentiate between the tertiary and quaternary structures of proteins.
b) What is meant by catalytic efficiency of an enzyme? Describe the mechanism of enzyme action.
5. a) What is the difference between vitamins and coenzymes? Why should our daily diet contain water soluble vitamins? Write the physiological functions of calcium, phosphorus, sodium and potassium.
b) Differentiate between cysteine and cystine. What is the role of cysteine in maintaining protein structure?
6. a) Describe and differentiate between substrate level phosphorylation and oxidative phosphorylation taking suitable examples for both.
b) Name two inhibitors of glycolysis and explain their mechanism of action.
7. a) Explain the following with respect to TCA cycle:
i) Substrate channelling
ii) Anaplerosis
b) Describe the regulation of pyruvate dehydrogenase complex by product inhibition.
8. a) Define photosystem and photophosphorylation in photosynthesis.
b) What is Hill reaction? Write the balanced equation for Hill reaction. Which photosystem is responsible for this?
9. a) Name one similarity and one dissimilarity between the action of DNA polymerase and RNA polymerase. Describe the transcription process.
b) Describe the scope of biotechnology. Describe the process of separation of penicillin in the final stage of production.
10. a) Describe the activation of amino acids during protein biosynthesis. How does an antibiotic affect protein biosynthesis?
b) List the different types of antibodies. What are the gross structural features of an antibody molecule? Name any three mechanisms by which antibodies interact with antigens.
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